国际眼科纵览 ›› 2022, Vol. 46 ›› Issue (6): 528-534.doi: 10.3760/ cma.j.issn.1673-5803.2022.06.010

• 综述 • 上一篇    下一篇

相干光断层扫描血管成像术在糖尿病视网膜病变检测中的应用

郭凯露  何珊  胡爱莲   

  1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 眼科学与视觉科学北京市重点实验室 100730
  • 收稿日期:2022-02-08 出版日期:2022-12-22 发布日期:2022-12-22
  • 通讯作者: 胡爱莲, Email: halzxf@126.com

Application of optical coherence tomography angiography in detecting diabetic retinopathy

Guo Kailu, He Shan, Hu Ailian   

  1. Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University; Beijing Key Laboratory of Ophthalmology & Visual Science,  Beijing 100730, China
  • Received:2022-02-08 Online:2022-12-22 Published:2022-12-22
  • Contact: Hu Ailian, Email: halzxf@126.com

摘要: 糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病并发的一种不可逆致盲性眼病,患病人数逐年上升。具有更宽视野、更长波长的广域扫描源相干光断层扫描血管成像术(optical coherence tomography angiography,OCTA)能够显示DR眼视网膜微动脉瘤在三维空间中的位置和形态、区分视网膜内微血管异常和新生血管,评估新生血管的活动状态。并且脉络膜毛细血管血流不足百分比能够预测DR进展,利于DR患者的早期筛查和对脉络膜的评估,有望替代FA成为诊断DR的工具。OCTA定量分析具有早期发现DR以及监测DR进展的潜力,并且OCTA定量数据输出为人工智能提供了独特的机会,有望为DR筛查、诊疗和随访建立新的、更便捷的工作流程。(国际眼科纵览,2022, 46:528-534)

关键词: 相干光断层扫描血管造影, 糖尿病视网膜病变, 人工智能

Abstract: Diabetic retinopathy (DR) is a kind of irreversible blindness caused by diabetes, and the number of patients is increasing year by year.Optical coherence tomography angiography (OCTA) with wider field of view and longer wavelength can display the location and shape of retinal microaneurysms in the three-dimensional space of DR eyes, distinguish retinal microvascular abnormalities and neovascularization,evaluate the activity of neovascularization, and the percentage of chorio capillaris flow deficit can predict the progress of DR. It is beneficial to the early screening and choroidal evaluation of DR patients and is expected to replace FA as a diagnostic tool for DR.OCTA quantitative analysis has the potential to detect DR early and monitor the progress of DR. Moreover,OCTA quantitative data output provides a unique opportunity for artificial intelligence,which is expected to establish a new and more convenient workflow for DR screening, diagnosis, treatment and follow-up. (Int Rev Ophthalmol, 2022, 46: 528-534)

Key words: optical coherence tomography angiography, diabetic retinopathy, artificial intelligence